Your AI Partner
at the Bench
Core Capabilities
Beyond Chat: Your Research Operating System
Not just a chatbot — an intelligent research platform that thinks, writes, and organizes like a scientist.
Step 1: Research
web_search("CRISPR yeast knockout 2024") sr_crispr01 sr_crispr02 sr_grna03
Step 2: Structure
CRISPR Knockout Plan
Guide RNA Design
Transformation Protocol
Screening Strategy
Step 3: Write
## Background
CRISPR-Cas9 enables efficient knockouts [1]
## HypothesisIf GC 40-60%, then efficiency >80% [2]
Deep Research
NewCreate research plans, technical routes, and experiment protocols with verified citations — not hallucinated URLs.
- Hypothesis-Driven Falsifiable hypotheses with quantitative thresholds
- Citation-Safe URLs verified from real search results, never hallucinated
- Incremental Building You control what gets expanded — no content overload
- User-Driven Pace AI suggests next steps, waits for your direction
Try asking:
Create a research plan for optimizing GFP expression in E. coli with multiple technical routes # Promoter Engineering
## Hypothesis
If we replace lac with T7, expression increases >5-fold [1]
## Protocol
Document Management
Organize your research with a hierarchical document system — plans, routes, experiments, and notes, all version-controlled.
- Hierarchical Organization Plans → Technical Routes → Experiments → Lab Notes
- Version Control Auto-snapshots on every edit, rollback anytime
- Sequence Embeds Reference sequences inline with directives
- 6 Document Types Plan, Technical Route, Experiment, Lab Notes, Literature Review, Custom
14 Document Tools:
create_document create_hierarchy get_outline get_section + 10 more
Linear Plasmid 3D Structure
pET28a-GFP 5,369 bp
GFP CDS T7 Promoter ColE1 ori
▼ ▼ ▼
1 1000 2000 3000 4000 5369
Sequence Design & Visualization
CoreA complete DNA design workbench — from sequence retrieval to cloning assembly, with interactive visualization and real-time analysis at every step.
Fetch & Create NCBI gene fetch, batch import, manual creation
Visualization Plasmid maps, linear views, feature annotations
Restriction Analysis Cut sites, digest simulation, site mapping
PCR Design Primer design, Tm calculation, tail addition
Assembly Gibson & Golden Gate with overlap design
Codon Optimization Host-specific optimization, CAI analysis
Manipulation Mutate, insert, delete, reverse complement
Export GenBank, FASTA, JSON, batch export
40+ Sequence & Analysis Tools:
fetch_gene design_primers restriction_sites codon_optimize gibson_assembly + 35 more
89+ Specialized Tools
Every Tool a Biologist Needs
Purpose-built tools for synthetic biology, from sequence manipulation to protein design.
Sequence Management
11 tools fetch_gene Fetch genes from NCBI by name, ID, or accession
fetch_genes_batch Batch fetch multiple genes at once
search_gene Search NCBI Gene database
create_sequence Create new DNA/RNA sequences
list_sequences List all sequences in session
get_sequence_info Get detailed sequence metadata
subsequence Extract sequence regions
reverse_complement Get reverse complement
concatenate Join sequences together
mutate Introduce point mutations
domesticate Remove internal restriction sites
PCR & Primer Design
4 tools design_primers Auto-design optimal primer pairs with Tm matching
calculate_tm Calculate melting temperature (nearest-neighbor)
add_primer_tails Add overhangs for cloning/sequencing
simulate_pcr Predict PCR products and verify primers
Cloning & Assembly
6 tools design_gibson_overlaps Design Gibson assembly overlaps
simulate_gibson_assembly Simulate and verify Gibson products
design_golden_gate_parts Design Golden Gate compatible parts
simulate_golden_gate_assembly Simulate Type IIS assembly
linearize_vector In silico vector linearization
assemble_parts Assemble standard biological parts
Sequence Analysis
10 tools restriction_sites Find all restriction enzyme cut sites
gc_content Calculate GC% with sliding window
find_orfs Detect open reading frames
codon_usage Analyze codon usage patterns
translate Translate DNA to protein
codon_optimize Optimize codons for expression host
calculate_cai Calculate Codon Adaptation Index
reverse_translate Convert protein to optimized DNA
align_sequences Pairwise sequence alignment
align_multiple_sequences Multiple sequence alignment (MSA)
Protein Design
9 tools fold_protein Predict 3D structure with ESMFold
fetch_alphafold_structure Fetch AlphaFold predicted structures
inverse_fold_protein Design sequences for target structure
analyze_protein_structure Analyze structural features
create_protein_sequence Create protein sequences
generate_protein AI-guided protein generation
guided_protein_generation Property-guided design
visualize_structure 3D structure visualization
list_proteins List all proteins in session
Benchling & Integrations
14 tools fetch_benchling_dna_sequence Import DNA from Benchling
register_benchling_dna_sequence Export DNA to Benchling
fetch_benchling_aa_sequence Import protein from Benchling
list_benchling_folders Browse Benchling folders
export_genbank Export to GenBank format
export_fasta Export to FASTA format
web_search Search scientific literature
lookup_protocol Find lab protocols
enzyme_info Get restriction enzyme details
Component Library
11 tools remember_component Save components for reuse
recall_component Retrieve saved components
search_components_advanced Search with filters
search_by_sequence_similarity Find similar sequences
get_standard_part Get standard BioBrick parts
list_standard_parts Browse parts registry
Document Management
13 tools create_document Create research documents
create_document_hierarchy Build document trees
get_document_outline Token-efficient outline view
update_document_content Edit document sections
search_documents Full-text document search
And many more specialized tools for your research workflow
View Full Tool Reference →Start Free, Scale as You Grow
No credit card required. Upgrade when you need more.
Free
$0 /month
Perfect for trying out Saion
- ✓ 50 messages/month
- ✓ Basic sequence tools
- ✓ Plasmid visualization
- ✓ GenBank/FASTA export
- ✓ 5 saved sequences
- × Deep Research
- × Protein folding
- × Benchling integration
Most Popular
Pro
$29 /month
For individual researchers and students
- ✓ Unlimited messages
- ✓ All 89+ tools
- ✓ Deep Research with citations
- ✓ Document management
- ✓ Protein folding (ESMFold)
- ✓ Component library
- ✓ Unlimited sequences
- ✓ Priority support
Team
$79 /user/month
For research groups and labs
- ✓ Everything in Pro
- ✓ Benchling integration
- ✓ Shared component library
- ✓ Team document sharing
- ✓ Admin dashboard
- ✓ SSO/SAML
- ✓ Audit logs
- ✓ Dedicated support
Frequently Asked Questions
Can I switch plans anytime?
Yes, upgrade or downgrade at any time. Changes take effect immediately.
Is there a student discount?
Yes! Students get 50% off Pro with a valid .edu email address.
What payment methods do you accept?
We accept all major credit cards and PayPal. Enterprise can pay by invoice.
Do you offer academic licenses?
Yes, contact us for special academic and non-profit pricing.